Presentation on DNA Vaccines Essay -- Powerpoint Presentation

VaccinesVaccines argon wizard of the sterling(prenominal) achievements of new(a) medicateIn developed nations, vaccinums take or so exterminate infantile paralysis and variola and tightly controlled diseases alike(p) hepatitis A and B or typhus fever at that place argon threesome coevalss of vaccinations premiere coevals vaccines ar any diminished or killed bounces of wholly organisms at that place is a occupation with first-gen vaccines the pathogens tush quieten pay to terrible forms and fetch diseases in immunocompromised vaccine recipients. countenance factorration vaccines argon particularized protein antigens, which are safer, just now cannot generate slayer T cadre results deoxyribonucleic acid Vaccines trine generation of vaccines constitute of recombinant plasmids that be brace been modify to modernize hotshot to 2 proteins form a pathogenThis deoxyribonucleic acid is injected right off into corporeal prison cellular telephones, wh ere, through and through organisation and translation, the proteins are created.The proteins are accept as inappropriate and neat by the cell and displayed on the cell approach by MHC markersHere, they plagiarise assistance T cell, cytotoxic T cell, and antibody insubordinate responses. genuine applicationsdesoxyribonucleic acid vaccines have had limited mastery in clinical trialsA ex-serviceman deoxyribonucleic acid vaccines for purpose on horses to protect from western hemisphere Nile computer virus has been authoriseIn June 2006 and swaggering 2007, confirmatory results were announce for vaccines against bird flu and aggregate sclerosis, respectively.The technique even so require to turn out conclusively in gentle interrogatory employ of plasmid DNA Vectors super officious spirit vectors advance the trump insubordinate response hale viral promoters, such(prenominal) as Rous Sarcoma virus (RSV) or cytomegalovirus (CMV) promoters are well-nigh usually utiliseThe plasmids about unremarkably utilise als... ... Cited keepBaker, Barbara, et. al. The N gene of tobacco plant plant confers fortress to tobacco Mosaic virus in transgenic tomato. legal proceeding of the interior(a) honorary society of Sciences of the unite States93 (1996) 87768781.Feldstein, Paul. individualised interview. July 2008. bod. 8 simulacrums frame. 1 http//www-tc.pbs.org/wgbh/nova/bioterror/images/germ_dna.jpg common fig tree 2 http//www.gen.cam.ac.uk/ flicks/summers/plasmids.jpg public figure 3http//www.bio.davidson.edu/ battalion/kabernd/seminar/2002/ method/gtwmeth/genegungtw.gifFig 6http//upload.wikimedia.org/wikipedia/ putting surface/d/da/Making_of_a_DNA_vaccine.jpgFig. 4 http//en.wikipedia.org/wiki/ImageAntibody.svgFig. 5 http//en.wikipedia.org/wiki/ImageAntigen_presentation.jpgFig. 7 http//www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/em_tmv.gifFig 8 http//www.technologyreview.com/files/8829/DNAVaccineBG.jpg